Withdrawal If you stop taking methadone, reduce the dose, or miss a dose, your body will react.This is because your body is accustomed to a certain level of methadone.You will then experience withdrawal symptoms. It may include: • Chills, shivering and sweating • Restlessness • Anxiety and anger • Crawling sensations in arms and legs • Sleep disturbances • Nausea and diarrhea • Runny eyes and nose • Pain in muscles, bones and joints • Yawning and sneezing Alcohol and sedatives Using alcohol, benzodiazepines, and other drugs alongside methadone is very dangerous and can cause harmful health effects, and in the worst case, be fatal. It can lead to a reduced effect of your methadone treatment. It will also impair your cognitive abilities, which in turn weakens your ability to rehabilitate. Methadone and other medications Tell your doctor if you are taking any other medications when starting treatment with methadone. Different medications can affect the effectiveness of methadone. If you have a new doctor or dentist who is not aware of your methadone treatment, make sure to tell them! It is always important that anyone treating you knows which medications you are using. If you have been prescribed other medications or purchase an over-the-counter medicine, you can always consult the pharmacy staff to see if these may affect your treatment with methadone. 8
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